Journal of Pharmacy and Pharmaceutical Research Open Access
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Abstract
A novel intracutaneous microneedle delivery system for the treatment of acute migraine
Hayley Lewis
A Novel Intracutaneous Microneedle Delivery System for
zolmitriptan has been developed by Zosano. This delivery
system provides: Rapid non oral delivery and pulsatile PK
profile, Room temperature stable formulations, Patient friendly
alternative to injection,Versatile delivery platform capable of
delivering large and small molecules, and vaccines. In a recent
clinical trial zolmitriptan intracutaneous microneedle delivery
system was highly effective for the treatment of migraine, with
statistical significance compared to placebo achieved for the
two co-primary endpoints of pain freedom at 2 hours and most
bothersome symptom absence at 2 hours.
