Journal of Drug Abuse Open Access

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Abstract

Biological (Testosterone and Oxytocin) Approach for the Impact of Naturalistic Cannabis use on Self-reported Opioid Withdrawal

Nader Charkhgard*, Shahram Naderi and Mohammad-Javad Morabbi

Testosterone and oxytocin, as two important hormones in the human body that have multiple functions, affect the process of consumption and symptoms of withdrawal syndrome. On the other hand, there are changes in the use of other substances, for example, the effects of cannabis use on these two hormones are completely contradictory to the effect of opioids on these two. Self-medication of patients using drugs is a common phenomenon, and here we examine the biological effects of this self-medication on drug withdrawal and the effects of cannabis on relieving withdrawal symptoms caused by the modulation of testosterone and oxytocin.