Norman Oneil Machado, Shahzad Younas, Mohamed Abdel Rahim, Abdullah al Jabri, Adil al Zadjali
Cystic mass presenting in the right hypochondrium, could be a diagnostic challenge. These lesions could arise from pancreas, common bile duct, liver, stomach and colon. Establishing a preoperative diagnosis with certainty, despite the modern radiological imaging and endoscopic facility may be difficult, particularly when it is due to an uncommon lesion like colon duplication cyst. We present here a case of a young lady who presented with one year history of abdominal pain. computerized tomography and magnetic resonance imaging scan revealed a large cystic mass, medial to the “C” loop of duodenum, mimicking a possible cystic lesion of the pancreas. Resection of the lesion and histopathology revealed a duplication cyst of the transverse colon. We discuss the various differential diagnosis of cystic lesion in the right hypochondrium and highlight the salient features of colonic duplication cyst.