American Journal of Advanced Drug Delivery Open Access

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Abstract

In vitro Evaluation of Antioxidant Activity of Michelia champaca (L.) Flowers

T. Ananthi and M. Chitra

The aim of the present study was to investigate the antioxidant activity of methanolic extract of Michelia champaca flowers. Antioxidant activity was evaluated by using in-vitro assay models like Total antioxidant capacity, Nitric oxide radical scavenging assay, Reducing Power Assay and Hydrogen Peroxide Scavenging Activity. All the antioxidant activities were compared with standard antioxidant such as ascorbic acid. Methanolic extract of the plant showed effective free radical scavenging activity at 300μg concentration. The IC50 values of the ethanolic extract of Michelia champaca flowers were found to be 260 μg in total antioxidant activity, 150 μg in nitric oxide radical assay, 240 μg in reducing power assay and 280 μg in hydrogen peroxide assay. The results obtained in this study showed that the flowers of Michelia champaca have antioxidant properties which provide a basis for the traditional use of the plant.