Since the SARS-CoV-2 pandemic began, every effort has been made to understand severe COVI-19 disease, which progresses to sepsis, multiple organ dysfunction, and septic shock. Mortality from the disease is exceeding 5 million patients in the world, only 5% of patients have severe or severe viral sepsis and enter intensive care, requiring; ventilatory, hemodynamic, vasopressor, antibiotic support and monitoring of biomarkers to be able to predict evolution and prognosis; the fatality in this group of patients is 40%. Sepsis, multiple organ dysfunction, and septic shock have been observed in all patients who die, however, sepsis is not always related to bacteria or co-infection in microbiological studies in these patients. This suggests that SARS-CoV-2 is the causative agent of this systemic condition and not bacteria. The objective of this article is to carry out a bibliographic review that allows us to know the final outcome of severe COVI-19 disease, whether it is due to immunological hyperactivity or due to bacterial co-infection.
Published Date: 2022-01-31; Received Date: 2022-01-03
