Longitudinal Adherence to Multi-Target Stool DNA Testing for Colorectal Cancer Screening is Poor

Anurag Maheshwari1; 2; Amol Agarwal1; 2; Feng Li1; Paul J Thuluvath1; 2

Abstract

Longitudinal Adherence to Multi-Target Stool DNA Testing for Colorectal Cancer Screening is Poor

Anurag Maheshwari1,2*, Amol Agarwal1,2, Feng Li1, Paul J Thuluvath1,2

We performed a retrospective study in a large community healthcare system. All patients (n=615) advised an initial mt- sDNA test in 2016 were reviewed. Patients with a negative test were eligible for the study (n=283); patients with a positive test (n=60) or non-compliance (n=272) were excluded. The primary outcome was longitudinal adherence, defined as the completion of a follow-up mt-sDNA test 2.5-3.5 years after the initial test result. Factors such as gender, age at initial test, race, body mass index (BMI), and insurance type were evaluated to determine their association with longitudinal adherence using logistic regression analysis. The Institutional Review Board determined the study was exempt from review, as it represented a quality improvement study.