Kulvinder Kaur
Painful nocturnal erections and idiopathic stuttering priapism are two known unique distinct entities in the physiopathology of erectile disorders. Since the latter in prolonged form or recurrent form can end up in the person developing irreversible erectile dysfunction we tried to conduct systematic review on these 2 rare disorders to update the etiopathophysiology to better manage the 2 conditions. Although lot of work is being done in animal models as far as sickle cell disease induced disorder is concerned still we await to know the proper etiopathophysiology of the idiopathic form and till we understand beyond the nitric oxide(NO)/cyclic guanosine monophosphate(cGMP)/ phosphodiesterase 5(PDE5) role we can only do relieving therapy using different drugs like hormonal drugs that cause hypogonadism, use of beta 2 mimetics like salbutamol or terbutaline surgical aspiration and injection of sympathomimetics like phenyl ephrine and detumuscence remains the only approach till we get some more evidence based therapies with future work on etiopathology
