Journal of the Pancreas Open Access

  • ISSN: 1590-8577
  • Journal h-index: 82
  • Journal CiteScore: 35.06
  • Journal Impact Factor: 24.75
  • Average acceptance to publication time (5-7 days)
  • Average article processing time (30-45 days) Less than 5 volumes 30 days
    8 - 9 volumes 40 days
    10 and more volumes 45 days

Abstract

Neurogenic Inflammation in Acute Pancreatitis

Akhil Hegde, Madhav Bhatia

Acute pancreatitis is a clinical condition whose incidence has increased over the past few years. The exact mechanism of its development is not yet clear. Substance P, the proinflammatory neuropeptide, has a role in the initiation of neurogenic inflammation. Substance P and its receptor neurokinin-1 receptor (NK-1R) are involved in the development of local as well as systemic inflammation in acute pancreatitis. This editorial focuses on the role of substance P and its receptors in the development of acute pancreatitis