Viktor Bekhterev
The solution of many problems in the analytical chemistry, ecology, hydrochemistry, biochemistry, pharmacology, toxicology are associated with the extraction and separation of the natural or synthetic organic compounds from aqueous media or from water-containing biological samples. In this report, a new approach to the isolation of hydrophilic organic substances from aqueous media in extractant is proposed: the extraction under the conditions of formation of the phase interface in the initially homogeneous system by thermal action.
A method of extractive freezing-out under the action of centrifugal forces (EFC) with the use of hydrophilic organic solvents has been developed [Patent RU2564999, Patent EP3357873]. The scientific basis of this method has been created, and the regularities of extraction of target components in the conditions of formation of the liquid – solid phase interface have been established. The EFC-methods in combination with GC and HPLC for determination of various organic substances are fast, cheaper and easier than QuEChERS. The expert's working conditions and safety have been improved by using a minimum amount of solvents.
A method of vapor-phase extraction (VPE) of organic substances from aqueous solutions is proposed [Patent RU2296716]. Its methodological foundations are developed, and the conditions for extraction of various substances are optimized. The partition coefficients of some hydrophilic and hydrophobic organic compounds in the water-extractant’s vapor system are determined. On the basis of theoretical representations for VPE the features of changing of the Gibbs energy are established in homological series of low-molecular carboxylic acids and phenols.
Based on this approach, new methods have been developed for determination of important analytes in water (natural and waste) and biological objects: drugs and narcotic substances in human urine, blood and organs, pesticides in the environment and food, food additives, biologically active substances in plants.
