European Journal of Experimental Biology Open Access
ISSN: 2248-9215
Journal h-index: 45
Journal CiteScore: 34.35
Average acceptance to publication time (5-7 days)
Average article processing time (30-45 days)
Less than 5 volumes 30 days
8 - 9 volumes 40 days
10 and more volumes 45 days
Reach us
+32 25889658
Abstract
Optimal Control of Bone Marrow in Cancer Chemotherapy
M. H. Noori Skandari, H. R. Erfanian, A. V. Kamyad and S. Mohammadi
We introduce an optimal method for controlling the bone marrow dynamics in cell-cycle-specific cancer chemotherapy. This method is based on measure theory and gives us the strategy applying drug where both bone marrow mass and the dose be maximized over the treatment interval. Using measure theory, the corresponding optimal control problem be transfer into a modified problem which is a type of an infinite dimensional linear programming problem whose its optimal solution can be approximated by optimal solution of finite dimensional problem.
