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Abstract

Post Ictal Psychosis in Drug-Resistant Epilepsy Responding to a Ketogenic Diet.

McManus E, McCoy Stacey, Lynch DPL, Beer WD, Phillips CLM 

Ketogenic diets mimic the metabolic profile of fasting, altering neuron energetics and stabilizing neuron synaptic function. They have an established role in the treatment of drug-resistant epilepsy(DRE). We present the case of a 30year-old male with an 18-year history of DRE and postictal psychosis; all attempts at seizure control failed until he was finally commenced on a ketogenic diet, which greatly reduced the seizure frequency. In addition to improved seizure control, his psychosis and anxiety symptomatology dramatically improved, resulting in a better quality of life.