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Abstract
Role of lncRNAs in Thyroid Cancer
Murali Krishna
Thyroid cancer is the most common endocrine cancer in the word and its incidence is on the rise. Though generally associated with a very good prognosis, few cases may demonstrate resistance to treatment such as radio-iodine therapy. lncRNAs have shown to be involved in several steps of thyroid carcinogenesis. It can act as a prognostic and diagnostic marker. Altered levels of specific lncRNAs have also shown to be associated with resistance to radioiodine treatment. Therapy with lncRNA has also shown to return radio-sensitivity in thyroid cancer cell lines.
