Javid Ahmad Bhat
Staphylococcus aureus is one of the most virulent microbial pathogen amongst gram positive bacteria to cause nosocomial and community acquired infections. An additional concern is the emergence and dissemination of nosocomial organisms with increased resistance to antimicrobial agents. Such microbes include methicillin resistant S.aureus (MRSA), S.epidermidis, vancomycin resistant Enterococci (VRE) and VISA. The development of vaccines and drugs that prevent and cure bacterial infections was one of the twentieth century’s major contributions to human longevity and quality of life. Antibacterial agents are amongst the most commonly prescribed drugs of any kind worldwide. Used appropriately, these drugs are lifesaving however, their indiscriminate use drives up the cost of health care leading to a plethora of side effects and drug interactions and fosters the emergence of bacterial resistance rendering previously valuable drugs useless.
