American Journal of Advanced Drug Delivery Open Access
ISSN: 2321-547X
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Abstract
Synthesis and Antimicrobial Activity of Some New 5-Oxo-Imidazolidine Derivatives
Vivek Gupta1, A. Pandurangan
Schiff bases are synthesized from paracetamol. 4-acetamidophenoxyacetylhydrazide is synthesized from paracetamol, which on reaction with various aldehydes gives Schiff bases. Schiff bases treated with amino-acetic acid to produce Imidazolidine derivatives. The entire synthesized compound characterized by physical and analytical data. The chemical structures of synthesized compound were confirmed by means of IR, 1HNMR and MS. Antimicrobial activity of synthesized compounds evaluated by cup-plate method. Synthesized compound showed good antimicrobial activity.
