Nasiru Pindiga Yahaya* and Augustine Umar
Schiff base metal Mn(II), Fe(II), Co(II), Ni(II) and Cu(II) complexes derived from 1(4-Chlorophenyl) ethanone and m-Hydroxyaniline (HL1) and Phenylethanone and m-Hydroxyaniline (HL2) were synthesized using reported methods. Complexes and the ligands were characterized using solubility, melting point, molar conductance and spectra compares of FTIR and Uv-visible. The solidity shows that the best solvents for all the complexes is DMSO and sparingly soluble in methanol and ethanol. The melting points of the complexes were higher than the parent ligands. The molar conductance reveals that all the metal complexes are non-electrolytes. The IR data for the HL1 shows that its coordination with metal ions in monodendated manner via the azomethine N-Donor site whereas the HL2 has coordinated to the metal ions in monodentate manner too via the azomethine N-Donor site The and Uv-visible spectra data hinted a significant information concerning the geometry and structure of the complexes which indicated that some of the complexes are octahedral and others are square planner in shape. The following bacteria Staphylococcus aureus, Salmonella typhi, Klebsiella pneumonia and Helicobacter pylori were screened with the Schiff base free ligand and their complexes, their activity confirmed that chelation increase antibacterial activity.
Published Date: 2022-10-17; Received Date: 2022-06-27
