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Commentary - (2023) Volume 10, Issue 4

Fatty Acid Overproduction by the Gut Commensal Microbiota Exacerbates Obesity
Keiichiro Matoba*
 
Department of Internal Medicine, The Jikei University School of Medicine, Japan
 
*Correspondence: Keiichiro Matoba, Department of Internal Medicine, The Jikei University School of Medicine, Japan, Email:

Received: 29-Mar-2023, Manuscript No. IPBJR-23-16747; Editor assigned: 31-Mar-2023, Pre QC No. IPBJR-23-16747 (PQ); Reviewed: 14-Apr-2023, QC No. IPBJR-23-16747; Revised: 19-Apr-2023, Manuscript No. IPBJR-23-16747 (R); Published: 26-Apr-2023, DOI: 10.35841/2394-3718-10.4.36

Description

Fatty acids are crucial components of our diet and play a vital role in various physiological processes. They are essential for energy production, hormone synthesis, and maintaining the integrity of cell membranes. While consuming an appropriate balance of fatty acids is crucial for optimal health, an imbalance can lead to several symptoms and health concerns. In this article, we will explore the symptoms of fatty acid imbalance, shedding light on the body’s messenger and its impact on our overall well-being. Fatty acids are organic molecules consisting of carbon chains with hydrogen atoms attached. They are categorized into three types: Saturated, monounsaturated, and polyunsaturated fatty acids. Saturated fatty acids lack double bonds and are typically solid at room temperature. Common sources include animal fats, dairy products, and tropical oils. Monounsaturated fatty acids contain one double bond and are primarily found in olive oil, avocados, and nuts. Polyunsaturated fatty acids have multiple double bonds and are found in fatty fish, vegetable oils, and certain nuts and seeds. Omega-3 and omega-6 fatty acids are types of polyunsaturated fatty acids that are essential for the body. Omega-3 fatty acids, such as Eicosapentaenoic Acid (EPA) and Docosahexaenoic Acid (DHA), are crucial for brain health, reducing inflammation, and supporting cardiovascular health. Omega-6 fatty acids, like Linoleic Acid (LA), play a role in immune function and cell signalling. Maintaining an appropriate balance between omega-3 and omega-6 fatty acids is essential for optimal health. However, the modern Western diet is often characterized by an excessive intake of omega-6 fatty acids compared to omega-3s. This imbalance can have profound effects on our well-being and contribute to the development of various health conditions. Omega-3 fatty acids possess anti-inflammatory properties, while excessive omega-6 fatty acids can promote inflammation. An imbalance between these fatty acids can lead to chronic inflammation, resulting in joint pain, stiffness, and swelling. Conditions such as arthritis, rheumatoid arthritis, and other inflammatory disorders can be exacerbated by this imbalance. The skin requires an adequate supply of omega-3 fatty acids to maintain its integrity and moisture levels. Insufficient omega-3 intake and an excess of omega-6 fatty acids can lead to dry, itchy skin and increase the risk of developing eczema. Omega-3 supplementation has shown promising results in managing these skin conditions. Omega-3 fatty acids are vital for brain health, as they contribute to the structure and function of brain cells. An imbalance between omega-3 and omega-6 fatty acids has been associated with cognitive issues, such as poor memory, difficulty concentrating, and increased risk of neurodegenerative disorders like Alzheimer’s disease. The brain relies on a balanced supply of fatty acids for neurotransmitter production and function. Omega-3 fatty acids, in particular, play a crucial role in maintaining healthy levels of neurotransmitters like serotonin, which is associated with mood regulation. Imbalances in fatty acids have been linked to mood disorders, including depression, anxiety, and bipolar disorder. An excessive intake of omega-6 fatty acids relative to omega-3s can disrupt the delicate balance required for optimal cardiovascular health. Omega-3 fatty acids help reduce triglyceride levels, lower blood pressure, and prevent the formation of blood clots. On the other hand, an imbalance can contribute to increased inflammation, arterial plaque formation, and an elevated risk of heart disease. While healthy fats are an important part of a balanced diet, an imbalance between fatty acids can impact weight management efforts.

Acknowledgement

None.

Conflict Of Interest

The author’s declared that they have no conflict of interest.

Citation: Matoba K (2023) Fatty Acid Overproduction by the Gut Commensal Microbiota Exacerbates Obesity. Br J Res. 10:36.

Copyright: © 2023 Matoba K. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.