Leonardo Roever1*, Elmiro Santos Resende1, and Giuseppe Biondi-Zoccai2,3,4
Federal University of Uberlândia, Department of Clinical Research, Brazil
Department of Medico-Surgical Sciences and Biotechnologies, Sapienza University of Rome, Latina, Italy
Eleonora Lorillard Spencer Cenci Foundation, Rome, Italy
VCU Pauley Heart Center, Virginia Commonwealth University, Richmond, VA, USA
Corresponding Author:
Leonardo S Roever-Borges
Federal University of Uberlândia
Department of Clinical Research
Bairro Umuarama, Uberlândia, Brazil
Tel: 553488039878
E-mail: leonardoroever@hotmail.com
Introduction
Clinical decision-making depends on a balanced judgment between the resources, tasks, skills and values, which in several times depends on external factors that cannot be easily controlled. Network meta-analysis is used to include all methods of synthesis that is extensive evidence, indirect comparison set, the comparison treatment mixture, and processing multiple meta-analysis [1-13] (Table 1).
| Network meta-analysis in intensive and critical care |
| Advanced Topics |
Future Perspectives |
Incorporating moderators: network meta-regression
Appraising between-study heterogeneity
Appraising inconsistency between direct and indirect estimates
Appraising small study effects and publication bias
Combining multiple effect estimates: multivariate network meta-analysis
Moving from study-level to patient-level data: individual patient network meta-analysis
State of the art reporting of network meta-analyses |
Moving from evidence synthesis to action The future of network meta-analysis: toward accessibility and integration |
Table 1 Describes the advanced topics and future perspectives of the network meta-analysis in intensive and critical care.
The future of network meta-analysis depends on the process of conducting a valid and effective systematic review, as well as the successful implementation of decision makers. This can provide new solutions to complex problems, from the evidence available to guide a more accurate clinical practice.
References
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