Perspective - (2022) Volume 7, Issue 9
Received: 31-Aug-2022, Manuscript No. IPIB-22-14530; Editor assigned: 02-Sep-2022, Pre QC No. IPIB-22-14530 (PQ); Reviewed: 16-Sep-2022, QC No. IPIB-22-14530; Revised: 21-Sep-2022, Manuscript No. IPIB-22-14530 (R); Published: 28-Sep-2022, DOI: 10.36648/2572-5610.22.7.100
Plant-based polyphenols are naturally occurring substances found in vegetables and fruits. Due to their nutraceutical and pharmacological roles in the prevention and treatment of human diseases, polyphenols have received particular attention in recent years. However, the main barriers to their use are their photosensitivity, low bioavailability, rapid metabolism, and short biological half-life. These obstacles could be overcome by encapsulating polyphenols both flavonoids and non-flavonoids into chitosan (CS)-tripolyphosphate (TPP) based nanoparticles (NP). The NP design’s ionic gelation method was the primary focus of this review. Ionic gelation’s application to the protection, controlled, and site-directed delivery of polyphenols is the subject of a comprehensive discussion and comparison in this contribution, which examines the findings of a decade’s worth of scientific publications.
Therefore, CS-TPP NP would serve as true platforms for transporting polyphenols or a combination of them, which could be utilized in the development of a brand-new class of drugs or nutraceuticals. There are at least 10,000 distinct compounds in the polyphenols family, a broad category of secondary metabolites found in plants. The development of polymeric structures- based site-directed or site-specific delivery systems has garnered a growing amount of interest in recent years. One of nature’s most abundant substances is polysaccharides. They are natural alternatives to synthetic polymers due to their low cost and widespread availability. Additionally, they are biodegradable, non-toxic, and safe materials. They can be used in a myriad of ways due to their various compositions (molecular weight, charge, polarity, solubility, etc.) that typically improve the encapsulated bioactive compound’s bioavailability. In recent decades, a burgeoning research field has paid attention to the study of the benefits of diverse polyphenols in the prevention and treatment of multiple chronic disorders, including neurodegenerative, retinal, cardiovascular, and intestine disease, diabetes mellitus, arthropathies, stroke, hypertension, atherosclerosis, obesity, cancer, and viral and bacterial infections, among others. Several attempts have been made to develop encapsulation systems that use these materials as encapsulating agents for the polyphenols were found to have antioxidant, anti- inflammatory, antibacterial, anti-fungal, antiviral, and anti-tumor properties in general. According to the presence of one or more hydroxyl groups linked to a benzene ring, polyphenols can be divided into two large group flavonoids and non-flavonoids that provide a summary of the two groups, their respective chemical structures, and the primary source from which they can be extracted.
In detergent formulations, sodium tripolyphosphate (STPP) provided a variety of advantages, including the ability to sequester calcium and magnesium, provide alkalinity, stabilize metal oxide colloid, and provide a substantial surface charge for peptization and suspension of other soils. Unlike STPP, builders, as we know them today, are primarily materials that bind and neutralize the negative effects of hardness (calcium and magnesium) ions in water or soil. As previously stated, these ions are harmful because they dissolve anionic surfactants like soap (which results in soap curd), LAS and AS. Hardness ions, on the other hand, have other negative effects. They may cling to soils or stains, which typically have a surface with a negative charge, and prevent their removal. Particulate and clay strains are particularly hard-hit by this effect. Hardness ions can also cause soil in the wash solution to flocculate and settle on fabrics. Hardness ion divalent nature is thought to be the source of “bridging” mechanisms.
Citation: Wang J (2022) Role of Tripolyphosphate Extracted from Bacterial Nucleotide used for Pharmacological. Insights Biomed. 7:100.
Copyright: © 2022 Wang J. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
