Acta Psychopathologica Open Access

Dr. Lei Pei

Biography

Dr. Lei Pei, Doctor of Science (Ph.D.-Science), now is a Lecturer of Basic medicine, in Department of Neurobiology, at Tongji Medical College, Huazhong University of Science and Technology. He had been worked in the Netherlands Institute of Neuroscience as the Visiting Scientist funded by China-Dutch Cooperative Program. He is the member of the The Chinese Neuroscience Society. Dr. Lei Pei got the Graduates Inovation Funds in 2007, and got the China-Dutch Cooperative Project Fund (09CDP022) in 2010. In addition, Dr. Lei Pei got the National Fund for Natural Science of China (NSFC) 81200863 and China Postdoctoral Science Foundation (CPSF) (2013M530345) in 2012 and 2013 respectively. Currently Dr. Lei Peis studies focus on three areas, first, mechanisms of cell death in cerebral ischemic stroke, second, mechanisms of inflammatory pain, and third, the mechanisms of the hypothalamus modulation on peripheral energy metabolism.

Research Interest

My specific areas of interest are Cerebral Ischemic stroke and very interested in identifying and characterizing the specific cellular and molecular signaling processes that cause the cell death and hoping for developing the practical strategies in the treatment of cerebral ischemic stroke. We successfully set up the MCAO mice model and other technique including primary neuron culture morphology, animal behavior, two photon imaging and molecular biology for studying the mechanisms of cell death after ischemic stroke. Inflammatory pain mechanisms and signaling pathway I am interested in tracing of fluorescence and attempting to observe the traced neurons innervating endodontium. Trigeminal ganglion (TG) neurons innervating endodontium are definitely pain sensitive and generally accepted as an ideal model for our pain study. My another interest involves applying neuroelectrophysiological skill (whole cell patch clamp) for measuring the current of traced neurons which might reflex the functional properties of the neurons sensing pain. In addition, we picked out the traced neurons and dealt with immunohistochemistry. This could reflex the morphological property of the neurons sensing pain.