Journal of Diabetes Research and Endocrinology Open Access

DECREASED LEVEL OF MELATONIN IN TYPE-2 DIABETIC PATIENTS AND INFLUENCE OF ADIPOSITY AND SMOKING

26^th International Conference on Clinical Diabetes

December 14-15, 2017 Rome, Italy

Peteris Tretjakovs, Ilze Konrade, Ieva Kalera, Normunds Limba and Gita Krievina

Riga Stradins University, Latvia University of Latvia, Latvia

Posters & Accepted Abstracts: J Diabetes Res Endocrinol

Abstract:

The Purpose of the present study was to evaluate the serum levels of melatonin in type-2 diabetic patients and to clarify whether there is an influence of adiposity and smoking. Patients & Methods: 26 type-2 diabetic (T2D) patients were recruited in the pilot study and 12 healthy subjects (non-smokers) were selected as controls (C). The study groups were matched for age and sex. Melatonin was measured in saliva by ELISA. Statistical analyses were performed using SPSS Statistic software. Results: Patients with T2D had significantly lower melatonin level than healthy control subjects (p<0.003), besides T2D patients with adiposity (BMI >30 kg/m2) had significantly lower melatonin level than patients without adiposity (p<0.035), as well as T2D smokers had significantly lower melatonin level than T2D non-smokers. Conclusion: T2D patients are associated with decreased melatonin level in saliva. Adiposity and smoking have influence on the decrease of melatonin concentration of T2D patients.

Biography :

Peteris Tretjakovs completed his PH.D. Currently he is a professor of physiology and the head of department of Human physiology and biochemistry at the Riga Stradins University in Latvia.