Journal of Infectious Diseases and Treatment Open Access

Extraction and antibacterial screening of mixture of Acalypha indica Linn and Tridax procumbens Linn

6^th Edition of International Conference on Antibiotics, Antimicrobials and Resistance

October 11-12, 2018 Edinburgh, Scotland

P Arulraj

RVS College of Pharmaceutical Sciences, India

Posters & Accepted Abstracts: J Infec Dis Treat

Abstract:

Aim: In the present investigation, antibacterial activity of ethanolic extract of mixture of the Acalypha indica and Tridax procumbens were studied. Materials & Methods: The antibacterial activity was assessed by cup and plate method and filter paper disc method by using Muller Hinton agar medium. The zone of inhibition of the concentrates of mixture of Acalypha indica and Tridax procumbens were compared with each other. The present investigation says that, as the concentration increases the zone of inhibition also increases. The antibacterial activity of the mixtures of Acalypha indica and Tridax procumbens, alcoholic extract was assessed by using cup and plate method. Results: The 2 mg/ml of the mixture produce 3.5 mm in Staphylococcus aureus and E.Coli. The 4 mg/ml of the mixture produce 4 mm in Staphylococcus aureus and 4.5 mm of E.Coli. 8 mg/ ml of the mixture produce 9.5 mm of Staphylococcus aureus and 10.5 mm of E.Coli. Hence, the above finding says that 8 mg/ml mixture of Acalypha indica and Tridax procumbens plant extract shows good activity. The antibacterial activity of the mixtures of Acalypha indica and Tridax procumbens, alcoholic extract was assessed by using filter paper disc method. 2 mg/ml of the mixture produce 3.5mm in Staphylococcus aureus and E.Coli. The 4mg/ml of the mixture produce 4mm in Staphylococcus aureus and 4.5mm of E.Coli. 8mg/ ml of the mixture produce 10.5mm of Staphylococcus aureus and 9.5mm of E.Coli. Hence the above findings says that 8 mg/ml mixture of Acalypha indica and Tridax procumbens plant extract shows good activity. Conclusion: The findings confirm that the traditional therapeutic claims for this plant, in near future surely be able to replace the conventional anti-bacterial agents to which there is increased incidence of drug interactions and the study suggests that this plant is promising for development of phytomedicine for antibacterial properties.

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