Journal of Eye & Cataract Surgery Open Access

Optical coherence tomography-angiography (OCTA) biomarkers correlating disease status in branch vein occlusion

World Congress on Ophthalmology & Eye Surgery

August 16-17, 2018 Paris , France

Mohamed Attia Ali

Minia University, Minia, Egypt

Posters & Accepted Abstracts: J Eye Cataract Surg

Abstract:

Purpose: To objectively assess the macular vascular flow and density changes together with morphological changes in patients with branch vein occlusion using OCTA automated software algorithms. Study design: Retrospective observational case series. Setting: Ophthalmology Department, Minia University Hospitals, Minia, Egypt. Patients & Methods: 20 eyes from patients having branch vein occlusion (including upper and lower temporal branches) with 20 eyes of normal individuals as control were examined using OCTA (RTVue-XR Avanti; Optovue, Inc, Fremont, CA). Foveal avascular zone (FAZ) area, macular vessel density together with corresponding thickness and visual acuity (expressed as the logarithm of the minimum angle of resolution; Log-MAR) were measured in both groups and statistically compared. Different biomarkers; size of the cleared-out areas, sprouted new collaterals and vascular morphological distortion, could be identified and used to assess severity as well as treatment effects. Results: The mean FAZ (non-flow) area was significantly enlarged in all patients and showed positive correlation with the Log-MAR visual acuity. Statistically significant negative correlation between flow area and foveal thickness (r=-0.45, p=0.0033). Statistically significant positive correlation between UCVA and foveal thickness (r=0.47, p=0.025). Conclusion: OCTA provides a non-invasive imaging modality and helpful tool to quantify and follow macular micro-vascular changes in patients with branch vein occlusion; it could settle treatment guidelines based on biomarkers and indices detected in different cases.

Biography :

E-mail: