Depressive Disorder is not a passing blue mood but rather persistent feelings of sadness and worthlessness and a lack of desire to engage in formerly pleasurable activities. A complex mind/body illness, depression can be treated with drugs and/or therapy.major depressive disorder (sometimes also referred to as clinical depression or simply depression) must either have a depressed mood or a loss of interest or pleasure in daily activities consistently for at least a 2 week period. This mood must represent a change from the person’s normal mood. Social, occupational, educational or other important functioning must also be negatively impaired by the change in mood
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