Inflammation is not just something that affects the joints and connective tissues of the body. Recent studies have linked inflammation of the arteries to heart attack and stroke. While there are four major risk factors that may contribute to an increased risk of heart related illness or event, as many as 50% of all cases do not present with these classic markers. In these cases, doctors are linking inflammation of the arteries to the, sometimes, fatal effects of heart attack and stroke. Inflammatory markers are too non-specific to be a useful tool for diagnosing serious underlying disease and should rarely be used in this situation.