Hypoglycemia causes the pancreatic alpha cells to produce glucagon, which promotes hepatic glucose synthesis. Deregulated glucagon secretion is linked to type 2 diabetes, and elevated glucagon levels contribute to diabetic hyperglycemia. Endocrine cells of the pancreatic islets are known as alpha cells (α-cells). They make up to 20% of human islet cells, which synthesize and secrete the peptide hormone glucagon, which raises blood glucose levels.
Published Date: 2022-03-28; Received Date: 2022-02-21
