Thalassemia and Sickle Cell Department, Hippocratio General Hospital, Greece
Research Article
Seroprevalence for Measles Antibodies among Multi-Transfused Patients with Hemoglobinopathies: The Experience of a Thalassemia and
Sickle Cell Department in Greece
Author(s): Manganas Konstantinos*, Sophia Delicou, Myria Pougiouka, Aikaterini Xydaki, Maria Liosi, Denis Gubbini and Vasiliki Skandami
Background: Infections are frequent in patients with hemoglobinopathies and in recent years have become a
significant cause of morbidity and mortality in this group of patients.
Aims: The purpose of this study was to determine the immunity status to measles of patients with hemoglobinopathies
due to the recent revival of measles in Greece.
Methods: 75 multi-transfused patients were studied. Serum measles IgG antibody titers were measured by an
Enzyme linked immunosorbent assay to determine the measles immune status and document previous measles
infection in individuals without a prior history of immunization.
Results: All but one of the 31 patients who were born before 1970, date of the introduction of nationwide
vaccination, was antibody positive. Of the younger patients, 84% we.. View More»
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