Department of Colon, Rectum, and Anus Surgery Service, National Institute of Medical Sciences and Nutrition Salvador Zubiran, Mexico
Review Article
Development of a Predictive Mortality Scale in Patients with Neutropenic Enterocolitis: A Systematic Review.
Author(s): Rogelio Zayas Borquez*, Alfonso Fernandez Ramirez, Oscar Santes Jasso, Emmanuel Posadas Trujillo and Yoselin Julisa Sarabia Perez
Introduction: Neutropenic Enterocolitis (NE) is a severe complication in immunosuppressed patients, especiallythose undergoing intensive oncological treatments. Predicting mortality in these patients is crucial for optimizing clinical management and improving therapeutic outcomes.
Methods: We conducted a systematic review of 24 clinical studies, including 1,172 patients diagnosed with neutropenic enterocolitis. Data sources included PubMed and Google Scholar, with the last search performed on September 13, 2024. Studies were selected based on inclusion criteria, such as adult patients, availability of mortality data, and the use of G-CSF, while exclusion criteria included pediatric populations and case reports. Clinical variables analyzed included ICU admission, surgical management, comorbidities, severity of neutropenia, and diagnostic timing... View More»