Quality in Primary Care Open Access

Internal Medicine Department, Military Hospital of Tunis, Tunisia

Publications

• Case Report   
  Thrombotic microangiopathy associated to Sjogren?s Syndrome: case report and literature review
  Author(s): Arij Ezzouhour Yahyaoui*, Sameh Sayhi, Bilel Arfaoui, Nour Elhouda Guediche, Faida Ajili and Nadia Ben Abdelhafidh
  
  Introduction: Sjogren’s syndrome (SS) is an autoimmune disease characterized by ocular and oral dryness and a variety of other systemic manifestations. Thrombotic Microangiopathy (TMA) is rarely associated with SS. We report a case that illustrates this association in a female patient, who also presents autoimmune hypophysitis. Observation: A 65-year-old patient was referred for investigation of an axonal sensorimotor neuropathy that has been evolving for 5 months. Possible infectious and neoplastic causes were ruled out by examination, laboratory tests and imaging. The patient reported ocular and oral dryness. Minor salivary gland biopsy highlighted the presence of focal lymphocytic sialadenitis with a focus score of 1 foci/4 mm2. Schirmer’s test was inferior to 5 mm/5 min in both eyes. Laboratory investigations revealed anterior pituitary failure including seconda.. View More»
  

  DOI: 10.36648/1479-1064.32.1.05

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