Department of Pharmacy, Laureate Institute of Pharmacy, Himachal Pradesh, India
Review Article
Different Analytical Method used for the Estimation of Methotrexate in Rheumatoid Arthritis
Author(s): Sharma Anupam*, Ankalgi Amar Deep, Devi Arti and Ashawat Mahindra Singh
Rheumatoid Arthritis (RA) is an inflammatory autoimmune disease characterized by inflammatory polyarthritis,
which affects peripheral joints, especially the small joints of the hands and feet. Rheumatoid arthritis is an autoimmune
disorder which occurs when our immune system mistakenly attacks own body’s tissues. Chronic untreated
inflammation may promote joint disintegration and joint destruction. It was more often reported in the females
as compared to the males and may be caused at any stage of life. The various drug are used in the treatment of
Rheumatoid arthritis included the non-steroidal anti-inflammatory drugs, synthetic and biological Disease-Modifying
Antirheumatic Drugs (DMARDs), analgesic agents and non-pharmacological measure seeking to alleviate pain,
reduce the damage and preserve the joint function but Methotrexate is the most effective drug.. View More»
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