Department of Biomedical Sciences, University of Leon, Spain
Research Article
Impact of Neurofibromatosis 1 on Quality of Life Using the skindex-29 Questionnaire in a Spanish Population.
Author(s): Atallah Isis*, Ana M. Cieza Rivera, Carlos Lobato Fuertes, Tania Fernández-Villa and Vicente Martín
Background: Neurofibromatosis type 1 (NF1), the most common genodermatosis, predisposes affected patients to melanocytic lesions and benign tumors. NF1 is associated with a considerable esthetic and functional burden that may negatively affect patients’ quality of life (QoL).
Aim: This study aims to assess the clinical features of NF1 patients and evaluate their impact on QoL.
Methods: NF1 patients were identified from a public health database of a region in Spain. All patients underwent clinical and ophthalmological evaluation for NF1 features. QoL was measured with the Spanish version of the Skindex- 29 questionnaire. Logistic regression was performed to identify possible determinants of quality of life.
Results: 40 patients fulfilling NF1 NIH diagnostic criteria were recruited (a.. View More»
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