Department of Digestive and Interventional Endoscopy Unit, ASST Grande Ospedale Metropolitano Niguarda, Italy
Mini Review
Serological Rapid Test for Diagnosis of Sars-Cov-2 Works on Gastro-Intestinal Tissue Samples of Covid-19 Patients: Practical Aspects of Single Center Observational Study
Author(s): Lorenzo Dioscoridi*, Forti Edoardo, Pugliese Francesco, Cintolo Marcello, Bonato Giulia, Marianna Bravo and Mutignani Massimiliano
SARS-COV-2 infection spreading becomes a long and challenging medical question. The possibility to improve the
diagnosis of SARS-COV-2 infection in digestive endoscopy is important because gastrointestinal symptoms can be the
presenting symptoms of COVID-19. We tried to obtain a fast and “bedside” diagnosis of gastrointestinal COVID-19 by
performing serological rapid test to verify the presence of SARS-COV-2 in gastrointestinal mucosal specimens. From
the 3rd to the 31th January 2022, regular mucosal biopsies were taken from stomach, ileum or colon of 10 COVID-19
patients (7M, 3F, mean age: 49.7 years) and from 10 negative patients (6M, 4F, mean age: 50 years) according to
standard clinical indications.
One specimen for each patient was placed in a sterile test-tube with 5 drops of standard reagent for rapid serological
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