Department of Medicine, University of Brasilia, Brazil
Research Article
Conversion from hemodialysis to hemodiafiltration affects the innate immunity of individuals with chronic kidney disease
Author(s): Flávio José Dutra de Moura*, David da Silva Nunes, Beatriz Guterres Rodrigues de Sousa, Jaqueline Santos Ribeiro, Jonas Gonzaga do Nascimento, Amanda Macedo, Eloah Soares Povill Souza, Marcus Henrique Oliveira, Fernando Fontes de Souza, Vanessa Simioni Faria, Shirley Claudino Pereira Couto, Tatiana Karla de Santos Borges, Joel Paulo Russomano Veiga and Selma Aparecida Souza Kuckelhaus
Background: Once a diagnosis of chronic kidney disease (CKD) stage 5 is confirmed, possible treatments include
kidney replacement therapies, such as hemodialysis (HD) and hemodiafiltration (HDF). HD removes low-molecular-weight molecules, while HDF purges small and large molecules, favoring the reduction of oxidative stress.
Objectives: This study evaluated the hematological, biochemical and immunological parameters of individuals
with CKD treated with HD who later converted to HDF.
Methods: This is a descriptive, retrospective and comparative study carried out with 25 individuals whose HD
treatment was later converted to HDF (convenience sample).
Results: Data were analyzed in blood samples (cells and serum). Patient`s etiologies were type II Diabetes Mellitus
(DM) (48%) and Systemic Arterial Hypertensi.. View More»
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