Department of Pediatric Oncology, Haemato-oncology and Bone Marrow Transplantation, Sarvodaya Hospital, Faridabad, India
Research Article
Sickle Cell Disease in Burundi- An Un-explored Terrain?
Author(s): Dinesh Pendharkar* and Garima Nirmal
Introduction: Sickle Cell Disease (SCD) is one of the most common causes of mortality and morbidity in Africa. There is paucity of data on SCD from Burundi.
Methods: A cross-sectional study was conducted using a predetermined questionnaire that included socio-demographic characteristics, basis of diagnosis, common clinical scenarios, transfusion requirements, usage of hydroxyurea, usage of folic acid, and knowledge about bone marrow transplantation.
Results: Participants were 174 patients with SCD with male: Female ratio of 1:1. The median age was 10 years (1.3-42 years). The diagnosis of SCD was made by Emmel test in 139/168 (82.74%) and electrophoresis in 29/168 (17.26%) patients. Nearly 150/164 (91.4%) patients ≥ 1 episode of veno-occlusive crisis in the preceding year. Out of 165 patients, 77(45.8%) required.. View More»