Department of Veterinary, Wolaita Sodo University, Wolaita Sodo, Ethiopia
Review Article
Review on Diagnostic and Therapeutic Role of Monoclonal Antibodies
Author(s): Isayas Asefa Kebede*
Monoclonal antibodies are antibodies which have a single, selected specificity and which are continuously secreted by immortalized hybridoma cells. The monoclonal antibodies being directed against single epitopes are homogeneous, highly specific and can be produced in unlimited quantities. In animal disease diagnosis, they are very useful for identification and antigenic characterization of pathogens. Monoclonal antibodies are effective targeted therapeutic agents. The high specificity of the antibodies makes them ideal to reach their intended target and thus is useful to treat a variety of disease states. Being biological agents, the moAbs have their own profile of side effects like hypersensitivity, development of neutralizing antibodies, immune suppressions leading to enhanced possibilities of opportunistic infections... View More»
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