Department of pharmaceutical and Toxicological chemistry, Kazakhstan
Review Article
Prospects for Creating New Medicines Based on Nitrogen-Containing Organic Compounds
Author(s): Аkzhonas Ermekovna Khamitova* and Dmitriy Aleksandrovich Berillo
The search for new, effective and safe (low toxicity) medicines remains an urgent problem. Many compounds containing piperidine, morpholine and piperazine series are widely used in medicine and belong to the important group of biologically active compounds. The informational and literary search was conducted for the development of new nitrogen-containing heterocyclic biologically active compounds. This review summarizes the results of piperidine, morpholine and piperazine as potential sources of biologically active substances. To analyze the ways of chemical synthesis, to study the biological activity of new biologically active compounds based on nitrogen-containing organic compounds and to consider currently known drugs based on piperidine, morpholine and piperazine. Scientific papers, review articles and patents in the field of synthesis of piperidine, morpholine and piperazine deri.. View More»
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