Department of Child Health, Airlangga University, Surabaya, Indonesia
Research Article
Association between Adiponectin Gene rs2241766 Polymorphism and Dietary Patterns and Serum Adiponectin Levels among Javanese Adolescents with Obesity: A Cross-Sectional Study
Author(s): Christine Florens, Nur Aisiyah Widjaja* and Roedi Irawan
Objective: Adiponectin plays an essential role in the relationship between obesity and insulin
resistance. This study aimed to analyze whether serum adiponectin levels are associated with
adiponectin gene rs2241766 polymorphism and dietary patterns.
Methods: This cross-sectional study involved Javanese adolescents aged 13-18 years with obesity.
Obesity was defined according to the centers for diseases control and prevention 2000 criteria. Blood
samples were collected to determine serum adiponectin levels through enzyme-linked
immunosorbent assay and adiponectin gene rs2241766 polymorphism through polymerase chain
reaction restriction fragment length polymorphism. Dietary patterns were described using energy
consumption percentages from carbohydrates and fat, calculated from a 24-hour dietary recall for 2
consecutive day.. View More»