Department of Applied Mathematics & Information Sciences, Zewail City of Science and Technology, Egypt
Research Article
Efficacy of Platelet Rich Plasma after Skin Needling in the Treatment of Vitiligo
Author(s): Rofaida Mahmoud Abdelaty*
Vitiligo is an idiopathic disorder in which the selective destruction of skin melanocytes results in the development of depigmented patches. It affects 0.5-1 % of the general population without any racial, sexual or regional differences in prevalence. The etiology of vitiligo has not yet been fully established; therefore, different factors are said to be potentially involved, including autoimmune, neural, genetic and biochemical hypotheses.
Platelet rich plasma (PRP) is the autologous preparation of platelets in condensed plasma. Various growth factors, including a platelet-derived growth factor, a transforming growth factor, a vascular endothelial growth factor, and an insulin-like growth factor, are excreted from a-granules of condensed platelets triggered by aggregation inducers.
These factors are known to control many processes, including cell migration, attach.. View More»
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