Department of Pediatrics and Child Health, Mbarara University of Science and Technology, Mbarara, Uganda
Research Article
Clinical Profiles and Survival of Children with Acute Lymphoblastic Leukemia in South West Uganda.
Author(s): Stella Zalwango*, Peters Kalubi, Siyadora Ankunda and Barnabas Atwiine
Background: Acute Lymphoblastic Leukemia (ALL) is the commonest childhood cancer globally. We described the
clinical features at diagnosis and established the overall survival of children diagnosed with ALL at our Pediatric
Cancer Unit.
Methods: In August 2020, we retrospectively studied children <16 years diagnosed with ALL, over a 4-year period
(June 2016 to May 2020) at Mbarara Regional Referral Hospital (MRRH) in South West Uganda. Frequencies and
proportions of baseline clinical features and treatment outcomes were described. Kaplan-Meier analysis and Cox
proportional hazard regression model were performed to estimate overall survival and identify its predictors respectively.
Ethical approval was obtained from Research Ethics Committee of Mbarara University of Science and
Technology and waiver given for consent.
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