Department of Neurological Surgery, University of Southern California (USC), Los Angeles, USA
Research Article
Transcranial Magnetic Stimulation for Schizophrenia: A Meta-Analysis
Author(s): Alexander Chen*, Matthew McCarron, Lauren Schooner, Kaevon Brasfield, Jordyn Chesley, Mark Ashla, Selam Mulugeta, Andrew Tung, Carlos Figueroa, Steven J. Siegel, Melissa L. Wilson and Darrin J. Lee
Background: Schizophrenia is a significant cause of morbidity, and current biologic treatments often fail to achieve
remission. Repeated transcranial magnetic stimulation (rTMS) is a non-invasive neuromodulation therapy approved
for major depression. Peer-reviewed literature suggests that rTMS may have efficacy for psychosis as well
as negative and cognitive symptoms; however, holistic data regarding the use of rTMS for schizophrenia remains
unclear.
Objective: We aim to synthesize published data of rTMS efficacy in treating schizophrenia and evaluate the most
efficacious treatment parameters.
Methods: A meta-analysis was performed evaluating mean weighted effect sizes (Cohen’s d) and heterogeneity
(Cochran’s I2).
Results: 24 studies were included for analysis (N=.. View More»
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